Endometrial Receptivity Analysis
Endometrial Receptivity Analysis
The Endometrial Receptivity Analysis (ERA) test is a pioneering new method of assessing when the endometrium (womb lining) is most receptive. This allows Clinicians to personalise the timing of embryo transfer to maximised chances of implantation.
Receptivity of the endometrium is a crucial factor in determining the success of IVF treatment. During IVF treatment, Clinicians have to estimate when the endometrium has reached the optimal time to introduce the embryo into the womb based on ultrasound scan results. This method does not always account for the differences in individual cycle patterns which means that not every woman’s endometrium will be at its most receptive at the same time. Three in every ten patients have displaced window of implantation.
By taking a small biopsy of the endometrium, the ERA test allows the analysis of 236 genes, to look for the genes that are vital to implantation that should be ‘switched on’ when the lining is receptive to receive an embryo. This then allows the timing of embryo transfer to be altered and personalised according to the ERA result to maximise the outcome.
This test has shown not to discriminate between fertile and infertile patients and it does not guarantee a successful outcome after personalised embryo transfer.
Frequently Asked Questions:
Until recently there has been no way of accurately assessing whether the endometrium is at its most receptive. Scientists now know that certain genes are ‘switched on’ when the endometrium is receptive and they can pinpoint these genes and check whether they are ‘switched on’ or not. This gives a good idea of whether the endometrium is ‘pre-receptive’, receptive’ or ‘post-receptive’. It gives specific personalised information regarding the optimal time for embryo transfer and increases chances of successful embryo transfer and of achieving high success rates.
It is particularly useful for women with repeated implantation failure as a displaced window of implantation is detected in approximately 25% of these patients.
The ERA test will be carried out in the month prior to the treatment cycle, and the results will determine the exact timing of the embryo transfer in the month of treatment. The results are vaild for up to 2 years.
To perform ERA it is necessary to take an endometrial biopsy from women in their natural cycle or hormone replacement therapy cycles, at a time corresponding to the phase of endometrial receptivity.
The endometrium is receptive when it is ready for the embryo implantation. This occurs around days 19-21 in each menstrual cycle of a fertile woman. This period of receptivity is called the window of implantation.
During a natural cycle this occurs seven days after the LH (Lutenising Hormone) surge OR after five full days of progesterone supplementation in Hormone Replacement Therapy (HRT) cycles. After the biopsy is taken it is immediately introduced into a tube, which contains fluid to preserve the tissue, and sent to IGENOMIX Laboratory in America for testing.
Once the sample is received by IGENOMIX, it takes 7-10 working days for the results to be available. Your results will be sent to you, and if requested your clinic, via email.
Monday - Saturday: £1200.00
Sunday: Not available
Please note a £100 non-refundable deposit is needed at time of booking an ERA Test with the balance to be paid on attendance. Scans and blood tests during the ERA cycle will be charged separately. ERA tests are not available on Sundays or Bank Holidays. (Please be aware the deposit is not transferable and is only valid for use within 4 months of purchase).
How do I book an Endometrial Receptivity Analysis (ERA) test?
Cherish-UK is a private pregnancy and fertility scanning clinic, you can self refer and arrange an appointment at your convenience. To book an Endometrial Receptivity Analysis (ERA) test please telephone us on 0121 354 4777 or 07580 611 879, fill out our online enquiry form or email us at firstname.lastname@example.org
What Our Clients Say
"I've met Jacqui here at Cherish on 3 occasions now, Jacqui gives you high standards of service, you automatically feel relaxed when you met her & is very clear with all she talks through with you, I will always return back here for all pregnancies, and most definitely highly recommend there friendly, professional service."
I cannot fault the service we received today. As soon as I arrived Diana made me feel at ease. Having being very worried this was very welcome. The scan was very detailed, I listened to the heartbeat and I came away with lots of photos and reassurance that at 10 weeks pregnant everything is as it should be. I would definitely use Cherish again for a scan in the future. Thank you!
I've had first came to Cherish when I couldn't get seen at my local EPU and Jacqui was so reassuring and supportive at such a vulnerable time. I've since returned for scans and an endometrial scratch in preparation for IVF cycles. Jacqui, Diana and Rachel offer a first class service and you never have a problem fitting me in for appointments at late notice. I wouldn't go anywhere else after experiencing your excellent care and service and you've all been so helpful and reassuring every time I visit. I hope that someday I'll be returning to have my pregnancy scans with you. Thanks ladies and I'll always recommend you to others.
Absolute amazing. Appointment same day I called, images and report within hours of appointment. Thank you so much
I visited Cherish via a referral from my private GP and I can only say good things about my experience. To say I was nervous beforehand is putting in lightly but from Rachel who made the appointment to Jacqui who conducted the scan, I was made to feel ease and not embarrassed. Which for me was hugely important as a previous scan with a private hospital was not handled so sympathetically or professionally.Each step of the scan was explained and the whole experience was made as painless as possible. The results emailed to me the same day, impeccable service, Thank you, Sam.
The ladies at Cherish are fantastic and so supportive. They do a brilliant and professional job and are also willing to do all they can to help you stay sane through what can be anxious times. Have been back numerous times for various reasons including scans, blood tests, administering medication and prescription requests, and will continue to go back despite the distance from my home. Thank you ladies
I have used Cherish for a number of services during my IVF cycles and have always found them to be extremely friendly and professional during what can be a stressful time. The services they offer have been invaluable to me whilst having IVF treatment abroad.
Excellent prompt service. Felt very relaxed and reassured.
I was experiencing some pain and very heavy cycles and I was quite worried. I have visited Cherish a few times and I must say that the service is outstanding. I had a gynaecology scan and I was reassured that everything was ok. Definitely recommend Cherish to everyone !
Had a really good experience today. Felt comfortable and made sure I was comfortable at all times. Gave really good advice on next step as well as reassuring me everything would be ok. I would recommend Cherish to anyone. Thank you for all you help xx
I had a gynaecology scan with Jacqui following a miscarriage 12 weeks ago. The hospital had unfortunately left me with many unanswered questions as to my ongoing bleeding and an abnormality found on a scan with no follow up arranged. Jacqui was great with us and we feel a lot more reassured. It was definitely worth it for the peace of mind. Thank you!
I had a most amazing experience seeing my baby at 7 weeks 3 days for the reassurance scan. Jacqui made sure everything was ok whilst doing the scan and was happy for me and husband to. I was then shown how a baby grows in each week. It was truly an amazing experience. Even managed to capture a video of the heartbeat. Would definitely recommend and would definitely come back for a gender scan.
Absolutely fabulous service when my husband and I had our reassurance scan. Diana was so lovely and made me feel really comfortable and at ease! Have already booked in for my next scan! Brilliant!
I had a Harmony test and a scan, as according to NHS test results, there was a higher risk of Down Syndrome. We were really anxious and wanted to be sure that our baby is fine. I was a lot calmer after the scan. Diana was wonderful, she answered all my questions, checked everything, let me listen to baby's heartbeat and even gave me lots of pictures. The results came very quickly (low risk), so I can enjoy my pregnancy without stress. I really recommend Cherish and this test, it's worth every money to know that your baby is fine!
We visited Cherish for the Harmony Test after having a previous Edward's syndrome baby. Diana was very kind and understanding of our anxieties. She was patient with us and explained everything in detail. Results were emailed back to us after a week as promised. Facilities were clean and quiet. We would highly recommend.
It's been a year since our little boy arrived into the world, and we could not have embarked upon the journey of IUI and, later IVF, without the support of Jackie and Diana from Cherish. From the tests needed for the clinic in Denmark, to follicle tracking scans, they met all of our treatment needs and did so in the warmest way, always making us relaxed and comfortable. No last minute appointment (needed before flights could be booked or medication could be taken) was ever too much trouble. We could think of no better place to find out our baby was healthy with an early scan or that we were expecting a boy at 16 weeks. This review is long overdue, but we wish to thank you ladies for helping to make our dreams come true. We wish you every success with Cherish - the women of the midlands rely on you and your incredible service! Katy and Fay
What a wonderful service, very friendly Jackie provided us more details about mine pregnancy then I found from my previous 4 NHS scans. Plus Diana delivered to us Panorama test results which made us the most happy future parents.
With a scary start of pregnancy I did not know what to expect at the scan. Even when I walked in i found it calming and a nice atmosphere to be in. Jacqui greeted me and is so so lovely. She put me at ease and scan went perfectly! All my worries went away. I would recommend this company to anyone, you do a brilliant job. Thank you so much.!
I had such great care from Cherish at two separate scans. I needed a scan to check lining for embryo transfer and I was fitted in at short notice and given lots of information. I was so impressed and if the transfer is successful I will be using Cherish for an early scan.